Publications by authors named "Nathan W Pearlman"
Background: A positive sentinel lymph node (SLN) is the most important prognostic factor for predicting survival in cutaneous melanoma. This study aimed to evaluate how the addition of single-photon emission computed tomography (SPECT) and computed tomography (CT) to planar lymphoscintigraphy (PL) alters SLN identification, yield, and localization of metastatic nodes in head and neck melanoma.
Methods: This retrospective review examined patients undergoing SLN biopsy for cutaneous melanoma of the head and neck between July 2003 and December 2015.
Article Synopsis
- Patients with recurrent pelvic cancer often face limited treatment options, and while surgery is one potential approach, it carries significant risks.
- A study analyzed patients who underwent specific surgical procedures for recurrent malignancies, using preoperative imaging to assess pelvic volume and related complications.
- Findings showed that a significant majority experienced complications post-surgery, and lower pelvic volume was linked to a heightened risk of infections, though overall mortality remained low.
Benign multicystic peritoneal mesothelioma (BMPM) is a rare peritoneal tumor. Surgery is the only effective treatment for BMPM, and affected tissues occasionally must be sacrificed to achieve adequate debulking. A 25-year-old female was diagnosed with BMPM.
View Article and Find Full Text PDFBackground: The external ear represents a site with high ultraviolet exposure and thin skin overlying cartilage. The aim of this study was to determine if ear melanomas have different characteristics than cutaneous melanomas in other anatomic sites.
Methods: The evaluation of patients treated at a tertiary care center.
Objective: To analyze the predictors and patterns of recurrence of melanoma in patients with a negative sentinel lymph node biopsy result.
Design: Retrospective chart review of a prospectively created database of patients with cutaneous melanoma. SETTING Tertiary university hospital.
Background And Objectives: Despite decreasing frequency, local recurrences of unresectable colorectal cancer (CRC) remain difficult problems. These patients have few treatment options with conventional therapy. Preliminary results of sequential radiofrequency ablation (RFA) and surgical debulking (thermo-surgical ablation) suggest this technique may have benefit.
View Article and Find Full Text PDFBackground: Treatment options for patients with inoperable primary or recurrent/metastatic abdominopelvic malignancies are limited, and these patients have short lifespan. The purpose of our study is to examine outcomes of combined open radiofrequency ablation (RFA) and surgical debulking of otherwise unresectable tumors.
Methods: Consecutive 50 patients were identified from an Institutional Review Board (IRB)-approved database undergoing ablation for unresectable abdominopelvic malignancies via conventional surgical methods in a single institution between 07/2003 and 09/2009.
Background: A positive sentinel lymph node (SLN) biopsy is an indication for completion lymph node dissection (CLND) in malignant melanoma; however, most CLNDs are negative. We hypothesized SLN metastatic size of < or =2 mm would predict CLND status and prognosis.
Methods: We evaluated 80 consecutive patients undergoing CLND for positive SLNs over a 10-year period.
Background: Advanced abdomino-pelvic tumors are often unresectable using surgery alone. The current study evaluated a combination of radiofrequency (RF) ablation (RFA) and surgical debulking for such lesions.
Methods: Between July 2003 and November 2004, we treated 16 patients.
Background: Posteriorly fixed anorectal cancer is often considered incurable, but may be resectable using transsacral approaches.
Methods: We reviewed 45 patients undergoing transsacral exenteration for this problem since 1983 to determine outcome of such surgery.
Results: The group consisted of 38 men and 7 women; 17 had primary tumors, 28 had recurrent cancer: local excision, 1; low anterior resection, 11; or abdominoperineal resection, 16.