Publications by authors named "Nathan Sagasser"

Article Synopsis
  • Granuloma annulare is a skin condition that can be difficult to treat, especially in its generalized form, affecting about 15% of patients.
  • Two women, aged 60 and 41, had severe cases that didn't respond to standard treatments like steroids and antibiotics.
  • Both patients showed significant improvement after taking upadacitinib, with one achieving complete clearance of lesions in 2 months and the other following suit within 4 months, suggesting a potential new treatment option.
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Dupilumab, a systemic injectable biologic, can be prescribed to patients with atopic dermatitis who do not respond to topical treatments. Atopy can frequently subside by blocking inflammatory pathways, such as interleukin-4 (IL-4) and interleukin-13 (IL-13) in the immune system. Dupilumab is generally well-tolerated and mild; the most common adverse reactions listed are arthralgia, back pain, and conjunctivitis, which clears upon cessation or finalization of dupilumab therapy.

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