Verification of a method to detect glass microspheres via micro-CT.

Introduction: The ability to determine the microscopic distribution of glass microspheres in Y radioembolization has important applications in post-treatment microdosimetry and cluster analysis. Current methods are time-intensive and labor-intensive and thus are typically only applied to small samples.

Materials And Methods: A high-resolution micro-CT image with a voxel size of 8.

Development of a Customizable Hepatic Arterial Tree and Particle Transport Model for Use in Treatment Planning.

Optimal treatment planning for radioembolization of hepatic cancers produces sufficient dose to tumors for control and dose to normal liver parenchyma that is below the threshold for toxicity. The non-uniform distribution of particles in liver microanatomy complicates the planning process as different functional regions receive different doses. Having realistic and patient-specific models of the arterial tree and microsphere trapping would be useful for developing more optimal treatment plans.