Publications by authors named "Nathan M Canaday"
Article Synopsis
- - A study compared the effectiveness of two types of hyperimmune plasma—PNAG HIP and RE HIP—in protecting foals from R. equi pneumonia, showing that PNAG HIP had better lab results but had not been tested in real-world conditions.
- - In a controlled clinical trial involving 460 foals, both groups received transfusions of either RE HIP or PNAG HIP shortly after birth and were monitored for pneumonia symptoms.
- - The findings revealed no significant difference in pneumonia development between the two groups, indicating that PNAG HIP is not more effective than the established RE HIP for preventing the disease in foals.
The efficacy of transfusion with hyperimmune plasma (HIP) for preventing pneumonia caused by Rhodococcus equi remains ill-defined. Quarter Horse foals at 2 large breeding farms were randomly assigned to be transfused with 2 L of HIP from adult donors hyperimmunized either with R. equi (RE HIP) or a conjugate vaccine eliciting antibody to the surface polysaccharide β-1→6-poly-N-acetyl glucosamine (PNAG HIP) within 24 hours of birth.
View Article and Find Full Text PDFTransfusing foals with Rhodococcus equi hyperimmune plasma (REHIP) is a standard practice at many horse-breeding farms to help prevent R. equi pneumonia. At many large breeding farms, pneumonia is most commonly recognized as subclinical based on thoracic ultrasonography findings.
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