Dose-response relationship between device-measured physical activity and incident type 2 diabetes: findings from the UK Biobank prospective cohort study.

Background: Most studies investigating the association between physical activity (PA) and the risk of type 2 diabetes are derived from self-reported questionnaires, with limited evidence using device-based measurements. Therefore, this study aimed to investigate the dose-response relationship between device-measured PA and incident type 2 diabetes.

Methods: This prospective cohort study included 40,431 participants of the UK Biobank.

Association between walking pace and incident type 2 diabetes by adiposity level: A prospective cohort study from the UK Biobank.

Aims: To investigate the combined association of adiposity and walking pace with incident type 2 diabetes.

Methods: We undertook a prospective cohort study in 194 304 White-European participants (mean age 56.5 years, 55.

Associations of grip strength and walking pace with mortality in stroke survivors: A prospective study from UK Biobank.

Introduction: Although stroke is an emerging cause of disability and mortality globally, associations between physical capability markers and mortality in stroke survivors are elusive. This study investigated the individual and combined associations of walking pace and grip strength with all-cause and stroke mortality in stroke survivors.

Methods: Individual and combined associations of walking pace and grip strength with stroke deaths and all-cause mortality were investigated using Cox proportional-hazard models adjusted for sociodemographic, lifestyle, and health-related variables.

Identifying the Biomarker Profile of Pre-Frail and Frail People: A Cross-Sectional Analysis from UK Biobank.

Objective: This study aimed to compare the biomarker profile of pre-frail and frail adults in the UK Biobank cohort by sex.

Methods: In total, 202,537 participants (67.8% women, aged 37 to 73 years) were included in this cross-sectional analysis.