Publications by authors named "Nathan Lu"

Objective: Management of mandibular ballistic trauma is poorly delineated, given the variable injury complexity. This study examines surgical outcomes and presents a novel scoring system to define and guide the management of low-velocity ballistic mandibular fractures.

Methods: A retrospective chart review was performed from 2015 to 2022 to collect data on patients who suffered ballistic mandibular fractures.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess how much useful information is available on pediatric otolaryngology fellowship websites and the ASPO program directory for prospective applicants.
  • Out of 36 accredited programs, all had accessible websites via Google, but they only covered an average of 6.9 out of 16 important criteria for applicants, similar to the ASPO directory.
  • The findings suggest that both resources are lacking in key information, and enhancing them could better support applicants in their decision-making process.
View Article and Find Full Text PDF

Biophysical factors play a fundamental role in human embryonic development. Traditional in vitro models of organogenesis focused on the biochemical environment and did not consider the effects of mechanical forces on developing tissue. While most human tissue has a Young's modulus in the low kilopascal range, the standard cell culture substrate, plasma-treated polystyrene, has a Young's modulus of 3 gigapascals, making it 10,000-100,000 times stiffer than native tissues.

View Article and Find Full Text PDF
Article Synopsis
  • Subperiosteal orbital abscesses (SPOAs) are common complications of acute bacterial sinusitis, particularly affecting children, and are usually treated conservatively unless patients do not improve.
  • This study analyzed data from 82 pediatric patients with medial SPOAs to establish a size threshold for predicting the need for surgical drainage.
  • Findings indicated that abscesses wider than 3.6 mm were significantly more likely to require surgical intervention, while no difference was found in drainage needs based on the abscess location (anterior vs posterior).
View Article and Find Full Text PDF

Introduction: Botox is frequently used for sialorrhea in patients with compromised airways and those with etiologies causing difficulty with secretion management (i.e. strokes, neurologic disorders, etc.

View Article and Find Full Text PDF

Purpose: A novel "Modified TCA Alloderm™ Myringoplasty" (TCA myringoplasty) technique for reconstruction of uncomplicated chronic tympanic membrane (TM) perforations is described.

Materials And Methods: Descriptive surgical technique for TCA myringoplasty on 12 total patients from 1/1/2020 to 12/31/2020. 3 patients were excluded for incomplete records.

View Article and Find Full Text PDF

Objective: Investigate incidence and natural history of otologic and sinonasal disease associated with 22q11.2 deletion syndrome.

Study Design: Case series.

View Article and Find Full Text PDF

Pyriform aperture stenosis (PAS) and choanal atresia (CA) are 2 anatomic causes of newborn nasal obstruction. The goal of management of PAS and CA is to establish a patent nasal airway, often requiring surgery. No previous study has sought to assess the long term sinonasal and otologic disease incidence and outcomes in the PAS and CA population after surgical intervention.

View Article and Find Full Text PDF

Extracellular signal-regulated kinase (ERK) is a member of the mitogen-activated protein kinase family of signaling molecules. ERK is predominantly found in two forms, ERK1 (p44) and ERK2 (p42), respectively. There are also several atypical forms of ERK, including ERK3, ERK4, ERK5 and ERK7.

View Article and Find Full Text PDF