Severe COVID-19 infection: An institutional review and literature overview.

Background: Our study aimed to describe the group of severe COVID-19 patients at an institutional level, and determine factors associated with different outcomes.

Methods: A retrospective chart review of patients admitted with severe acute hypoxic respiratory failure due to COVID-19 infection. Based on outcomes, we categorized 3 groups of severe COVID-19: (1) Favorable outcome: progressive care unit admission and discharge (2) Intermediate outcome: ICU care (3) Poor outcome: in-hospital mortality.

Cancer treatment refusal decisions in advanced cancer: a retrospective case-control study.

Objective: Cancer remains one of the leading causes of death worldwide. Despite advancements in anticancer therapy, some patients decide against treatment. Our study focused on characterising therapy refusal in advanced-stage malignancies and further determining if certain variables significantly correlated with refusal, compared with acceptance.