Publications by authors named "Nathan Kirsch"

Pneumonia is a common disease-causing hospitalization. When a healthcare-associated infection is suspected, antibiotics that provide coverage for multi-drug resistant (MDR) or extended-spectrum beta-lactamase (ESBL) bacteria are frequently prescribed. Limited data is available for guidance on using meropenem as a first-line empiric antimicrobial in hospitalized patients with risk factors for MDR/ESBL bacterial infections.

View Article and Find Full Text PDF

 This study was aimed to familiarize obstetricians with the legal environment surrounding Effexor lawsuits and emphasize the importance of documenting informed consent in the medical records when prescribing a medication that is being targeted for litigation.  We used the LexisNexis legal search engine to review legal documents from Effexor-related cases and also used Google to search for Effexor-related lawsuits online, further researching these cases via publically available court records from district clerk offices. Finally, we conducted a year-by-year literature review from 1993 to 2017 to establish the history and evolution of scientific studies surrounding Effexor use during pregnancy.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to analyze how taking medications during early pregnancy affects the fetal fraction (FF) levels in women undergoing cell-free DNA (cfDNA) testing, comparing those on medications to those not on any medications.
  • - Results showed that women taking two or more medications had significantly lower FF levels compared to those not taking medications, with obesity also negatively impacting FF levels.
  • - Specifically, metformin was linked to a 1.8% reduction in mean FF, suggesting that both medication use and maternal obesity should be factored into discussions about cfDNA testing outcomes and their limitations.
View Article and Find Full Text PDF

 The gold standard for antenatal diagnosis of placenta previa is the transvaginal ultrasonography. In placenta previa cases, separation of placental and uterine tissues is challenging even for the most experienced surgeons. Life-threatening obstetrical complications from cesarean deliveries with placenta previa include peripartum hemorrhage, coagulopathy, blood transfusion, peripartum hysterectomy, and multiple organ failure.

View Article and Find Full Text PDF