Publications by authors named "Nathan K Jansen"
Article Synopsis
- Ebola virus disease (EVD) has a case fatality rate of about 50% due to outbreaks in Africa, highlighting the need for effective countermeasures tested on nonhuman primate (NHP) models.
- A study involving four rhesus macaques exposed to Ebola via aerosol revealed distinct disease stages: subclinical (high CO2 levels and lymphopenia), clinical (fever, viremia, and respiratory alkalosis), and decompensatory (coagulopathy, cytokine storms, liver and kidney injury), leading to shock and mortality.
- The aerosol model showed differences in disease progression compared to intramuscular methods, including a longer subclinical phase and shorter clinical phase, which suggests that rapid identification of symptoms
Drive-through coronavirus disease 2019 screening can evaluate large numbers of patients while reducing healthcare exposures and personal protective equipment use. We describe the characteristics of screened individuals as well as drive-through process and outcome measures. Optimal drive-through screening involves rapid turnaround of test results and linkage to follow-up care.
View Article and Find Full Text PDFLeprosy, or Hansen's disease (HD), is caused by the bacterium and is a significant cause of morbidity worldwide. Clinical manifestations range from isolated skin rash to severe peripheral neuropathy. Treatment involves a prolonged course of multiple antimicrobials.
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