L. Stem Bark Attenuates Epileptic Seizure, Depression, and Neurodegeneration by Mediating GABA and Glutamate in Pentylenetetrazol-Kindled Rats.

Objectives: Epilepsy is a neurological condition characterized by repeated seizures attributable to synchronous neuronal activity in the brain. The study evaluated the effect of acetone extract of stem bark (ASBE) on seizure score, cognition, depression, and neurodegeneration as well as the level of Gamma-Aminobutyrate acid (GABA) and glutamate in Pentylenetetrazol-kindled rats.

Methods: Thirty-five rats were assigned into five groups (n = 7).

Food irradiation: an effective but under-utilized technique for food preservations.

While food borne pathogens constitute a major public health problem world-wide, food post-harvest losses is considered to be the leading cause of hunger and malnutrition globally. Food irradiation is a process of preserving food in which food are exposed to appropriate doses of ionizing radiation in order to kill insects, molds and other potentially harmful microbes and allergens. The process involves carefully exposing food to a measured amount of ionizing radiation in a special processing room on a conveyor belt for a specified duration.

Genistein and L. prevent oxidative stress and upregulate proglucagon and insulin receptor mRNA in diabetic rats.

Type 2 diabetes occurs as a result of insulin resistance and dysfunction in insulin signaling. Controlling hyperglycemia and activation of insulin signaling are important in the management of type 2 diabetes. This study aimed to evaluate the effect of genistein and L.