The most common equine tapeworm, , has often been neglected amongst molecular investigations and has been faced with limited treatment options. However, the recent release of a transcriptome dataset has now provided opportunities for in-depth analysis of protein expression. Here, global, and sub-proteomic approaches were utilized to provide a comprehensive characterization of the soluble glutathione transferases (GST) (ApGST).
View Article and Find Full Text PDFAnn Allergy Asthma Immunol
October 2008
Background: One of the characteristic features of the hyperresponsive airway smooth muscle in asthma is the loss of deep-inhalation bronchoprotection and bronchodilation. The airway of individuals with asthma is also characterized by inflammation.
Objective: To evaluate whether the loss of deep-inhalation bronchoprotection is correlated with the degree of inflammation in the asthmatic airway.
Background: Two bronchoprovocation methods are widely used. Compared to the tidal breathing method, the dosimeter method delivers approximately half the dose and involves five deep inhalations. Both the lower dose and the bronchoprotective deep inhalations contribute to the lesser airway response of the dosimeter.
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