Publications by authors named "Nathalie Marchay"
Genes Chromosomes Cancer
March 2014
Article Synopsis
- The study explored whether sex chromosome loss (SCL) is related to aging or linked to chronic lymphocytic leukemia (CLL), finding that SCL occurred in 2.3% of CLL cases.
- In half of the cases with SCL, it was the only cytogenetic abnormality identified, and fluorescence in situ hybridization (FISH) confirmed the presence of SCL in 5-88% of the cells tested.
- SCL was significantly associated with deletions of 13q, especially when both alleles were affected, suggesting that SCL may play a role in the development of CLL.
