Publications by authors named "Nathalia C F Fagundes"
This study aimed to evaluate the level of oral health knowledge among teachers in a city of the Brazilian Amazon region (Belem, Pará) and explore the association between teachers' knowledge and their proposed actions in the event of dental trauma accidents within the school environment. The descriptive cross-sectional study involved 170 elementary teachers from public schools in the Metropolitan Region of Belem, Para State, Brazil. A self-administered questionnaire with multiple-choice questions was utilized to assess teachers' oral health knowledge across various domains.
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- Recent literature highlights the growing use of social media in oral health education, but there's a lack of comprehensive summaries on this topic.
- A scoping review analyzed 40 English-language studies published from 2008 to 2023, mainly focusing on undergraduate dental students and identifying YouTube as the most utilized platform for educational purposes.
- Findings suggest that while social media can be useful in oral health education, there is a need for stronger research designs to accurately assess its impact.
Article Synopsis
- The study aimed to investigate how orthodontists (OTs) and pediatric dentists (PDs) in Brazil screen and manage pediatric obstructive sleep apnea (OSA).
- A survey was conducted with 381 dental professionals, and 10 in-depth interviews were performed to gather insights on their practices and perceptions regarding OSA.
- Findings revealed that many OTs and PDs had some knowledge of OSA, utilized sleep questionnaires, and often provided specific treatments, but they faced barriers and expressed a need for better resources and guidelines in managing OSA.
Article Synopsis
- This systematic review investigated the link between apical periodontitis (a dental condition) and systemic biomarkers in adults, using established research protocols like PRISMA.
- The study evaluated 656 initial articles, ultimately including 17 after applying specific eligibility criteria, and assessed their methodological quality, revealing varying levels of bias among them.
- Findings indicated a significant association between apical periodontitis and specific inflammatory biomarkers, such as interleukins (IL-1, IL-2, IL-6) and immunoglobulins (IgG, IgM), primarily measured in blood plasma and saliva.
Article Synopsis
- Numerous studies have investigated the effects of fluoride (F) on various systems, especially its interaction with the thyroid, but a clear consensus is still lacking.
- This systematic review aimed to collate evidence regarding the impact of fluoride levels in drinking water on thyroid function, focusing on studies recognized by the World Health Organization.
- Out of 3,568 studies, only seven met the criteria, with five indicating that high fluoride exposure may harm thyroid function; however, all studies had significant methodological issues leading to low confidence in the findings.
Objectives: To explore parents' experiences and perceptions regarding engagement in health services for managing residual paediatric obstructive sleep apnoea (OSA) across levels of care.
Methods: Qualitative description guided study design. Data were collected through semi-structured interviews with parents of children diagnosed with residual OSA at a university-based sleep clinic.
Changes in biomarkers levels from gingival crevicular fluid in pre- and postmenopausal women undergoing orthodontic treatment : A systematic review.
J Orofac Orthop
August 2024
Article Synopsis
- This study investigates differences in biomarker levels in the gingival crevicular fluid of premenopausal versus postmenopausal women receiving orthodontic treatment.
- After a thorough search across multiple databases, three relevant studies were identified, focusing on levels of biomarkers such as RANKL, OPN, and IL-17A.
- Results indicated some differences in biomarker levels between the groups, but the limited number of studies and variability in findings call for more in-depth research to validate these conclusions.
Is there an association between periodontal disease and root caries? A systematic review and meta-analysis.
PLoS One
November 2023
Article Synopsis
- * Researchers analyzed 1,725 studies but found only four that met eligibility criteria, which were then assessed for bias and confounding factors.
- * The findings indicated that adults with periodontal disease have a 1.38 times higher likelihood of having root caries compared to those without, although the certainty of this evidence is considered very low.
Article Synopsis
- - This systematic review and meta-analysis investigated the link between periodontal disease (PD) and athletic performance in professional athletes, using studies published until April 2022.
- - After reviewing 793 references, only eight studies qualified, and while two showed no correlation between PD and athletic performance, a meta-analysis involving 396 participants indicated a significant association between PD and a self-reported drop in sports performance.
- - The findings suggest that periodontal disease could negatively impact athletes' performance, but more research is necessary to better understand the relationship and assess other influencing factors.
Article Synopsis
- Obesity is a significant public health issue, with food consumption decisions heavily influenced by individual taste perceptions, impacting eating behaviors and body weight.
- The study reviewed various research articles to assess the connection between obesity and taste alterations by analyzing data from multiple electronic databases, resulting in the inclusion of 19 relevant studies.
- Findings indicate that 40% of eligible studies showed a link between obesity and altered taste perceptions, with most studies demonstrating good methodological reliability, although some limitations exist in the research.
Objective: This scoping review aims to describe dental treatment-related patient-reported outcomes (dPROs) while using oral appliances (OAs) to manage obstructive sleep apnea (OSA) in children and adults.
Methods: Available literature that assessed dPROs in children and adults with OSA managed through OAs. Any clinical studies were included without restrictions of year or country.
Article Synopsis
- Molar-incisor hypomineralization (MIH) is an enamel defect affecting some molars and incisors, potentially caused by systemic and environmental factors, including respiratory diseases.
- * This study aimed to examine the relationship between MIH and respiratory diseases by reviewing literature, ultimately identifying 13 relevant articles from an initial pool of 3,666.
- * The findings indicated that children with MIH are more likely to have respiratory diseases compared to those without MIH, but the overall evidence quality was rated as very low.
Temporomandibular Joint Dysfunction (TMD) is an umbrella term that includes musculoskeletal and neuromuscular conditions affecting the temporomandibular joint. The present systematic review aimed to verify whether there is a specific association between TMD and anxiety. The searches were carried out in electronic databases, including PubMed, Scopus, Web of Science, and LILACS, without restrictions on publication date and language.
View Article and Find Full Text PDFThis systematic review aimed to assess whether dental caries is associated with oxidative salivary stress. The searches were carried out in electronic databases, including PubMed, Scopus, Web of Science, the Cochrane Library, LILACS, OpenGrey, and Google Scholar, without restrictions on the date of publication and language. The acronym PECO was used, in which the participants (P) were children and adolescents exposed (E) to dental caries compared (C) to those without dental caries, with the outcome (O) of modulation of oxidative biochemical parameters.
View Article and Find Full Text PDFUnlabelled: Salivary content has been reported as a potential biomarker for oxidative stress assessments especially in context of exercise-induced oxidative stress. This systematic review following PRISMA guidelines aimed to evaluate the effects of physical exercise and changes promoted in oxidative stress identified in saliva.
Methods: Studies published up to May 2022 were searched in online databases (PubMed, Scopus, Web of Science, The Cochrane Library, LILACS, OpenGrey, and Google Scholar).
Introduction: Obstructive sleep apnoea (OSA) is a sleep-breathing disorder that seems likely to have long-term negative social and health consequences in children and adolescents. There are no established standard management approaches when the first line of therapy, the tonsillectomy and adenoidectomy (T&A), is not indicated or fails to address paediatric OSA (residual paediatric OSA). This protocol describes a prospective cohort study that aims to assess the effectiveness of orthodontic interventions for managing residual paediatric OSA in patients with concomitant craniofacial issues.
View Article and Find Full Text PDFStudy Objectives: This review aimed to evaluate the association between craniofacial features in children and adolescents with pediatric obstructive sleep apnea (OSA).
Methods: Seven databases were searched to fulfill our research objectives. Clinical studies that included participants younger than 18 years with fully diagnosed OSA or without OSA and that evaluated skeletal, soft craniofacial features, or dental arch morphology were considered for this review.
Article Synopsis
- Different studies have linked fluoride exposure to potential neurological disorders in children, but clinical evidence on specific neurological effects has been inconsistent and controversial.
- A systematic review and meta-analysis of 4,024 studies narrowed down to 27 relevant ones, primarily examining IQ changes associated with fluoride from sources like fluoridated water.
- The analysis indicated a correlation between high fluoride exposure and IQ impairment in individuals, but found no significant evidence of neurological disorders at low exposure levels, highlighting the need for further research due to the weak quality of existing evidence.
Purpose: This review aimed to evaluate the effects of oral appliance (OA) therapy on serum inflammatory cytokines in adults diagnosed with obstructive sleep apnea (OSA).
Methods: Seven electronic databases and partial gray literature were searched without restrictions through March 2021. Articles evaluating the levels of serum inflammatory cytokines in patients with OSA after OA treatment were included.
Article Synopsis
- Periodontitis is a complex disease influenced by various factors, including immune response and psychological conditions, and this review explores its potential link to anxiety in adults.
- Researchers analyzed 11 observational studies out of over 6,000 to assess the relationship between periodontitis and anxiety, finding that most studies indicated higher anxiety levels in those with periodontitis, though one had a high risk of bias.
- The overall evidence regarding anxiety's impact, evaluated with the GRADE tool, was deemed low, highlighting the necessity for more extensive research on this association over time.
Neurodegenerative diseases are a group of progressive disorders that affect the central nervous system (CNS) such as Alzheimer, Parkinson, and multiple sclerosis. Inflammation plays a critical role in the onset and progression of these injuries. Periodontitis is considered an inflammatory disease caused by oral biofilms around the tooth-supporting tissues, leading to a systemic and chronic inflammatory condition.
View Article and Find Full Text PDFLead exposure and its association with neurological damage: systematic review and meta-analysis.
Environ Sci Pollut Res Int
July 2021
Lead (Pb) is one of the most toxic and abundant elements in the earth's crust, which is pointed out that the intoxication caused by it may damage biological systems. This systematic review with meta-analysis aimed to evaluate the association between Pb exposure and neurological damage. This work was executed according to PRISMA guidelines, and seven online databases were consulted.
View Article and Find Full Text PDFThe significant contribution of dental professionals to the management of selected adult obstructive sleep apnea (OSA) cases is understood. Among children, it has also been suggested that dental professionals may also help screen and manage this morbidity in selected cases. It has also been noted that our understanding of pediatric OSA lags significantly behind adult OSA.
View Article and Find Full Text PDFDiabetic retinopathy is a common microvascular complication in diabetic patients and is considered the main cause of visual loss worldwide. Periodontitis is a chronic inflammatory condition, which compromises dental supporting tissues. The chronic bacterial challenge in periodontitis is a persistent source of inflammatory mediators that may be associated with insulin resistance, increasing the risk of complications of diabetes mellitus.
View Article and Find Full Text PDFThis systematic review and meta-analysis aimed to investigate a possible association between stress and bruxism in humans. This study was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines under the code CRD42020188862, and the searches were performed on the following databases: PubMed, Scopus, Web of Science, Cochrane, LILACS, OpenGrey, and Google Scholar. This systematic review evaluated observational studies in adult humans with and without stress to verify the association between bruxism and the presence of stress.
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