Publications by authors named "Natasja Van Gasse"
Background: Prolonged shedding of SARS-CoV-2 in immunocompromised patients has been described. Furthermore, an accumulation of mutations of the SARS-CoV-2 genome in these patients has been observed.
Methods: We describe the viral evolution, immunologic response and clinical course of a patient with a lymphoma in complete remission who had received therapy with rituximab and remained SARS-CoV-2 RT-qPCR positive for 161 days.
The current study compared the QuantiFERON-TB® Gold Plus on LIAISON® XL to the T-SPOT.TB for the diagnosis of latent Mycobacterium tuberculosis infection on 125 patient samples. A high agreement of qualitative results (90%) was observed between both methods with 3% major discrepancies, half of which were false negative results with the T-SPOT.
View Article and Find Full Text PDFWe report on sample IS/17575 since it generated highly divergent results in the Belgian SARS-CoV-2 serology external quality assessment scheme. Sample IS/17575 was serum originating from a 30 years old male patient. 124 diagnostic laboratories analysed this sample.
View Article and Find Full Text PDFBackgroundIn Belgium, rubella serology is frequently requested in women of childbearing age, despite high vaccination coverage and a near-absence of congenital rubella cases. Different test kits are available and should be standardised by an international standard preparation.AimTo analyse and compare rubella serology practices in Belgian laboratories.
View Article and Find Full Text PDFArticle Synopsis
- Current diagnosis of legionellosis relies heavily on urinary antigen testing (UAT) for Legionella pneumophila serogroup 1 (Lp1), but this method often misses non-Lp1 infections.
- A study reviewed results from 14 Belgian laboratories, revealing that 44.4% of UAT results were false negatives and were reclassified as legionellosis using PCR testing.
- The findings highlighted that 39.4% of legionellosis cases could have been overlooked or delayed without a syndromic testing approach, emphasizing the advantages of molecular methods, particularly in lower respiratory tract samples.
Objectives: To determine the role of perinatally acquired Candida colonization to invasive Candida infection (candidemia) and to assess risk factors associated with Candida colonization and candidemia in neonatal intensive care unit patients.
Design: Retrospective case-control study.
Setting: Neonatal intensive care unit of a teaching hospital.