Publications by authors named "Natasja H A M Denissen"
Article Synopsis
- There is a need for a standardized method to measure disease activity in patients with psoriatic arthritis, leading to the development of the 3-item Visual Analogue Scale (3VAS) and 4-item Visual Analogue Scale (4VAS).
- A study involving 629 patients was conducted to assess the validity and responsiveness of these scales compared to other established measures, revealing significant correlations and responsiveness similar to existing standards.
- The findings suggest both scales perform well in identifying disease activity, with the 4VAS potentially being the better option due to its improved face validity.
Patient-reported outcomes in newly diagnosed early rheumatoid arthritis patients treated to target with a tocilizumab- or methotrexate-based strategy.
Xavier M Teitsma Johannes W G Jacobs Paco M J Welsing Attila Pethö-Schramm Michelle E A Borm Natasja H A M Denissen
Rheumatology (Oxford)
December 2017
Objective: To evaluate the effect of initiation of tocilizumab, with or without MTX, compared with MTX alone on patient-reported outcomes (PROs), in DMARD-naïve patients with early RA.
Methods: In U-Act-Early, patients initiated treat-to-target step-up MTX, tocilizumab or tocilizumab plus MTX therapy. PROs assessed included the Functional Assessment of Chronic Illness Therapy-Fatigue, 36-item Short Form (SF-36), five dimensional EuroQol (EQ-5D) and the Revised Illness Perception Questionnaire.