Publications by authors named "Natasha De Silva"
Article Synopsis
- The introduction of the HPV immunisation programme in England is expected to significantly decrease the occurrence of vaccine-type infections among young women.
- A study analyzed HPV prevalence in young females under 25 before the mass vaccination began in 2008, using residual swab samples collected during chlamydia testing programs.
- The findings revealed that 35% of participants aged 16-24 had high-risk HPV infections, with higher rates linked to factors like age and sexual behavior, highlighting a concerning prevalence of HPV before the vaccination rollout.
Article Synopsis
- Persistent infections with high-risk HPV can lead to cervical and other cancers, while low-risk types are linked to genital warts, prompting an investigation into the prevalence and risk factors associated with various HPV types in men and women.
- Data from the British National Survey of Sexual Attitudes and Lifestyles (1999-2001) revealed that 29.0% of women and 17.4% of men tested positive for HPV DNA, with HR-HPV found in 15.9% of women and 9.6% of men.
- The study highlighted strong correlations between HR-HPV and risky sexual behaviors, such as having multiple partners or not using condoms, emphasizing the need for ongoing monitoring of HPV prevalence
The ability to detect type-specific high risk HPV (HR-HPV) infections in samples from females and males is important for monitoring the epidemiology of HPV and the impact of vaccination. Type-specific detection concordance between paired urine and genital samples from females (n = 264) undergoing routine colposcopy and males (n = 88) attending a genito-urinary medicine clinic was evaluated using an in-house genotyping assay. The overall inter-rater agreement (κ) was 0.
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