How do malfunctioning onsite wastewater systems influence water quality? Assessing treatment of nutrient and Escherichia coli in central North Carolina.

Onsite wastewater systems (OWSs) can be significant sources of nutrients and E. coli to water resources, potentially resulting in water quality degradation especially during times of malfunction. An OWS is considered malfunctioning when septic tank effluent is discharged into drainfield trenches during periods when there is insufficient separation to groundwater (<30 cm), when wastewater upwells to the surface, or when backup of wastewater into the tank or home occurs.

A methodological framework for assessing sea level rise impacts on nitrate loading in coastal agricultural watersheds using SWAT+: A case study of the Tar-Pamlico River basin, North Carolina, USA.

This study addresses the urgent need to understand the impacts of climate change on coastal ecosystems by demonstrating how to use the SWAT+ model to assess the effects of sea level rise (SLR) on agricultural nitrate export in a coastal watershed. Our framework for incorporating SLR in the SWAT+ model includes: (1) reclassifying current land uses to water for areas with elevations below 0.3 m based on SLR projections for mid-century; (2) creating new SLR-influenced land uses, SLR-influenced crop database, and hydrological response units for areas with elevations below 2.

Emerging role of mucins in antibody drug conjugates for ovarian cancer therapy.

Ovarian cancer stands as the deadliest gynecologic malignancy, responsible for nearly 65% of all gynecologic cancer-related deaths. The challenges in early detection and diagnosis, coupled with the widespread intraperitoneal spread of cancer cells and resistance to chemotherapy, contribute significantly to the high mortality rate of this disease. Due to the absence of specific symptoms and the lack of effective screening methods, most ovarian cancer cases are diagnosed at advanced stages.

Spatiotemporal water quality variability in a highly loaded surface flow wastewater treatment wetland.

This study evaluates spatiotemporal relationships between water quality parameters (WQPs), nutrients, suspended solids, and biochemical oxygen demand (BOD) concentrations within an engineered wastewater treatment wetland system in the Georgia Piedmont, USA. We explored factors related to treatment efficiency within a heavily loaded 630-m surface flow wetland system over a 2-yr period. Relationships between temperature, dissolved oxygen (DO), and oxidation-reduction potential (ORP) were observed; relationships were also seen between these WQPs and nutrient concentrations.

A case of pulmonary nodules in a patient living with HIV diagnosed with secondary syphilis.

We discuss a case of secondary syphilis with pulmonary involvement in a 45-year-old man who tested positive for HIV. He presented with dyspnoea, chest pain and a rash on his limbs and torso. A CT showed multiple bilateral necrotic lung nodules.

Potential Susceptibility of Six Aquatic Plant Species to Infection by Five Species of .

Investigations of the susceptibility of aquatic plants to species of are limited. Therefore, the objective of this study was to assess the potential susceptibility of six aquatic plant species, frequently used in constructed wetlands or vegetated channels, to infection by five species of commonly found at nurseries in the southeastern United States. In a greenhouse experiment, roots of each plant species (, , 'Rising Sun', , , and ) growing in aqueous solutions were exposed to zoospores of each of the species of (, , , , and ).

Molecular Detection and Characterization of Picobirnavirus in Environmental Water in Thailand.

Background: Enteric viruses are responsible for waterborne and foodborne infections affecting a large number of people around the world. Picobirnavirus (PBV) is a highly versatile virus, detected in a wide range of hosts and has been reported to be associated with gastroenteritis in humans and animals.

Methods: Molecular screening of environmental water samples for PBV was performed over a period of two years from November 2016 to July 2018.

Characterizing the Performance of Denitrifying Bioreactors during Simulated Subsurface Drainage Events.

The need to mitigate nitrate export from corn and soybean fields with subsurface (tile) drainage systems, a major environmental issue in the midwestern United States, has made the efficacy of field-edge, subsurface bioreactors an active subject of research. This study of three such bioreactors located on the University of Illinois South Farms during their first 6 mo of operation (July-Dec. 2012) focused on the interactions of seasonal temperature changes and hydraulic retention times (HRTs), which were subject to experimental manipulation.