Publications by authors named "Natasha Basma"
Objective: Lennox-Gastaut Syndrome (LGS) is a severe, often treatment-resistant epilepsy syndrome typically diagnosed in early childhood. Many have seizures before diagnosis. Some have periods of seizure freedom before treatment resistance, i.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to estimate the incidence of 28 rare epilepsies in children from New York City between 2010-2014 and compare these findings with existing literature.
- - Eight of the rare epilepsies had multiple prior estimates, and the researchers' findings were consistent with published data, identifying infantile epileptic spasms as the most common, while 15 had less data, resulting in new estimates for conditions like early infantile developmental encephalopathy.
- - The findings highlight a gap in research, particularly for genetic epilepsies with vague symptoms, suggesting the need for more comprehensive studies to clarify their incidence.
Objective: Administrative codes to identify people with rare epilepsies in electronic health records are limited. The current study evaluated the use of keyword search as an alternative method for rare epilepsy cohort creation using electronic health records data.
Methods: Data included clinical notes from encounters with International Classification of Diseases, Ninth Revision (ICD-9) codes for seizures, epilepsy, and/or convulsions during 2010-2014, across six health care systems in New York City.
Background: We summarize the history of individuals with Sturge-Weber syndrome (SWS) to inform clinical trial design and identify variations in care.
Methods: We performed retrospective chart review of individuals with SWS from centers in New York City. We characterized data quality using a novel scoring system.
Objective: Treatment delays for refractory convulsive status epilepticus (RCSE) are associated with worse outcomes. In the United States, treatment for pediatric RCSE is slower than guidelines recommend. To address this gap, the American Academy of Neurology and Child Neurology Society (AAN/CNS) developed a quality measure: the percentage of RCSE patients that receive third-line treatment within 60 minutes.
View Article and Find Full Text PDFBased on a multicenter cohort of people with anti-NMDA receptor encephalitis (anti-NMDARE), we describe seizure phenotypes, electroencephalographic (EEG) findings, and anti-seizure treatment strategies. We also investigated whether specific electrographic features are associated with persistent seizures or status epilepticus after acute presentation. In this retrospective cohort study, we reviewed records of children and adults with anti-NMDARE between 2010 and 2014 who were included in the Rare Epilepsy of New York City database, which included the text of physician notes from five academic medical centers.
View Article and Find Full Text PDFObjective: Sudden unexpected death in epilepsy (SUDEP) is an important cause of mortality in epilepsy. However, there is a gap in how often providers counsel patients about SUDEP. One potential solution is to electronically prompt clinicians to provide counseling via automated detection of risk factors in electronic medical records (EMRs).
View Article and Find Full Text PDF