Publications by authors named "Natasha Ann Keasberry"
Article Synopsis
- - The title compound features a nickel (Ni) atom that is coordinated by two tridentate ligands, resulting in a distorted octahedral structure.
- - The crystal exhibits monoclinic symmetry at 100 K and includes a mixture of water and methanol as part of its structure.
- - One ethyl group in the ligands shows disorder between two positions, and there are notable hydrogen bonds between the solvent molecules and the ligand groups.
This work reports on the first electrochemiluminescence (ECL) immunosensor employing a novel nanostructured composite of titanium dioxide (TiO) and gold nanourchins (AuNU) to detect protein allergen Ovomucoid (Ovm) found in eggs. TiO and AuNU were dispersed in Nafion and drop-casted onto SPGE with Tris(2,2'-bipyridyl)-ruthenium (II) ([Ru(bpy)]) and tri-n-propylamine (TPrA) served as strong luminophore/co-reactant pairs as a source of ECL signals. The linear range, limit of detection, reproducibility and practical applications of the sensor were assessed.
View Article and Find Full Text PDFIn this study, Gold-microrods (AuMRs), Pd-nanoparticles (PdNPs), and Polyaniline (PANI) nanocomposite-interface was fabricated on the screen-printed carbon-microelectrode (SPE). Each layer of the interface was characterised using field emission-scanning electron microscopy (FE-SEM) and cyclic voltammetry (CV). The fabricated SPE/AuMRs/PdNPs/PANI interface demonstrated the highest electronic current and showed excellent peroxidase-mimic towards HO using chronoamperometry (CA).
View Article and Find Full Text PDFArticle Synopsis
- - This study introduces a new electrochemiluminescence method for precisely measuring creatine kinase MB (CK-MB) using a special nanocomposite made from carbon nano-onions and metal nanoparticles like gold and iron oxide.
- - The immunosensor was created by layering the nanocomposite on an electrode, attaching an antibody, and using a specific luminophore and co-reactant for optimal light emission during testing.
- - It demonstrated an impressive detection range from 50 fg/mL to 10 ng/mL with a very low detection limit of 5 fg/mL, along with excellent selectivity and stability for potential clinical application in human serum samples.
Enzyme-linked immunosorbent assay (ELISA) is a popular detection technique for the screening and diagnosis of diseases. The sensitivity of ELISA can be increased by the incorporation of nanoparticles. Through this article, we discuss the utilization of nanoparticles in ELISA.
View Article and Find Full Text PDFNanoparticles have been widely developed and shown to have intrinsic enzymatic ability, and are used in biosensors. Compared to biological enzymes used in biosensors, which are expensive and tedious to harvest, enzyme-mimic nanoparticles or nanozymes are both more stable and sensitive. An important area in this work is the development of a simple detection principle of immunosensor based on the one-step synthesis of silver nanoparticle seeded onto a gold core.
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