Publications by authors named "Natascha Wolf"
Biomed Pharmacother
November 2024
Article Synopsis
- Chlamydia trachomatis is the most common bacterial STI globally, making vaccine development challenging due to its complex lifecycle and poor antigen delivery methods.
- Recent research focused on using bacterial protein bodies (PBs) to deliver vaccine antigens, specifically testing the efficacy of PBs containing specific Chlamydia antigens in mice.
- Results showed that the PB-CTH522-SP vaccine not only induced strong immune responses but also significantly reduced bacterial counts in mice after exposure to Chlamydia, suggesting PBs could be a viable platform for effective vaccine development.
