Publications by authors named "Natascha Bom"
Exploring the frequency of a TP53 polyadenylation signal variant in tumor DNA from patients diagnosed with lung adenocarcinomas, sarcomas and uterine leiomyomas.
Igor Araujo Vieira Guilherme Danielski Viola Eduarda Heidrich Pezzi Thayne Woycinck Kowalski Bruna Vieira Fernandes Natascha Bom
Genet Mol Biol
January 2024
Article Synopsis
- * In a study examining Brazilian patients with lung adenocarcinoma, sarcoma, and uterine leiomyoma, the minor allele (C) of this variant was found in only 1.02% of LUAD cases, while none were detected in SARC or ULM samples.
- * Although the prevalence of rs78378222 is low in the specific tumors studied, the findings suggest that further analysis in Brazilian regions is not necessary, but molecular testing for this variant should still be considered in other populations.