Publications by authors named "Natarajan Paarthipan"

Background: Müllerian anomalies significantly impact female reproductive health. This study aims to compare the diagnostic efficacy of three-dimensional ultrasound (3D-US) and magnetic resonance imaging (MRI) in detecting and classifying these anomalies.

Methods: A retrospective analysis of 150 patients with Müllerian anomalies was conducted at Saveetha Medical College and Hospital from March 2018 to March 2024.

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This case report describes a rare and complex instance of urinary bladder herniation into the scrotal sac, complicated by intrascrotal perforation. This condition, primarily seen in elderly, obese men, poses significant diagnostic and therapeutic challenges. The patient, an 83-year-old man with a history of obesity and chronic lower urinary tract symptoms, presented with acute scrotal pain and swelling.

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  • Lung masses can be benign or malignant, and Multi-detector CT (MDCT) plays a critical role in helping to differentiate between these types, although histopathological confirmation through biopsy is often necessary for a definitive diagnosis.
  • The study aimed to evaluate the diagnostic accuracy of MDCT in distinguishing benign from malignant lung masses and to correlate imaging findings with results from CT-guided biopsies.
  • Conducted over 17 months with 52 patients, the study used descriptive statistics to analyze the effectiveness of CT-guided biopsies and the diagnostic performance of MDCT in identifying thoracic lesions.
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  • Diffusion-weighted imaging (DWI) measures the motion of water protons in fetal tissues, notably assessing the apparent diffusion coefficient (ADC) values for various fetal organs and the placenta at different gestational ages.
  • The study included 103 singleton pregnancies from 20 to 38 weeks and used specific imaging parameters to evaluate ADC values in areas like the fetal brain, lungs, kidneys, and placenta.
  • Results showed significant variances in ADC values across brain regions and a positive correlation between white matter ADC values and gestational age, while no significant correlation was found for kidneys.
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  • Spinal dysraphism refers to a range of congenital spinal and spinal cord defects caused by incomplete neural tube closure during early development.
  • The text presents a case study of a 15-year-old male with various congenital spinal anomalies, emphasizing the complexity of his condition.
  • It highlights the importance of multimodal imaging, particularly MRI, in accurately diagnosing and managing these anomalies, which include issues like scoliosis and spina bifida occulta.
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Background Traumatic brain injury (TBI) remains a foremost cause of death and disability globally, with elevated intracranial pressure (ICP) being a crucial factor in patient outcomes. While invasive monitoring is the gold standard for assessing ICP, it carries risks and is not always feasible. This study proposes a novel noninvasive parameter using computed tomography (CT) imaging.

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Background Computed tomography pulmonary angiography (CTPA) is the standard diagnostic tool for evaluating patients with suspected pulmonary thromboembolism (PTE) in many institutions. This condition, whether acute or chronic, results in both partial and complete intraluminal filling defects, which exhibit sharp interfaces with intravascular contrast material. Acute PTE that leads to complete arterial occlusion may cause the affected artery to appear enlarged.

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Emphysematous osteomyelitis (EO) is a rare and severe bone infection characterized by the presence of gas within the bone and surrounding soft tissues, commonly caused by gas-forming bacteria. We present a case of an elderly patient with extensive EO due to  infection. The patient exhibited systemic signs of infection and severe localized pain.

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Pulmonary carcinoids, particularly the typical variant, are low-grade neuroendocrine tumors (NETs) known for their often indolent behavior. Their rare and atypical presentations can pose significant diagnostic challenges. We present a case of a 39-year-old female with no significant past medical history who presented with high-grade intermittent fever, chills, rigors, and breathlessness, with symptoms persisting for approximately 20 days.

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Introduction  Diffusion-weighted imaging (DWI) is a promising magnetic resonance imaging (MRI) technique for differentiating between benign and malignant breast lesions. This study set out to assess the diagnostic utility of DWI and apparent diffusion coefficient (ADC) values in the characterization of breast lesions. Materials and methods A retrospective analysis comprised 30 patients with breast lesions who had breast MRI with DWI.

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Introduction The pericardial fat pad, located anteriorly to the heart between the pericardium and myocardium, has garnered significant interest in cardiovascular research due to its potential role in the pathophysiology of various cardiac conditions. Despite its proximity to the myocardium, it is distinct from the epicardial fat depot found between the myocardium and the visceral layer of the pericardium. Studies have shown that excess pericardial fat is associated with an increased risk of heart failure and other cardiovascular diseases.

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  • Polyostotic fibrous dysplasia (PFD) is a rare, noncancerous bone disorder that results in abnormal bone formation, leading to deformities and functional issues.
  • A 32-year-old man was diagnosed with leontiasis ossea, a severe form of craniofacial fibrous dysplasia, after presenting with distinct facial abnormalities confirmed through imaging and tissue analysis.
  • The case highlights the challenges in diagnosing and treating PFD, emphasizing the importance of teamwork among healthcare professionals for effective patient management.
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Background Breast cancer remains one of the most common malignancies affecting women globally, contributing significantly to the disease burden. The advent of neoadjuvant chemotherapy (NAC) has revolutionized the treatment for locally advanced breast cancer, allowing tumors to be downstaged and making breast-conserving surgery (BCS) feasible. Accurate localization of the tumor bed post-NAC is crucial for successful surgical removal of residual disease.

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Introduction Obstructive jaundice due to proximal biliary obstruction presents significant diagnostic and therapeutic challenges. Accurate and timely diagnosis is essential for effective management. Objective/aim This study aimed to evaluate and compare the diagnostic accuracy of magnetic resonance cholangiopancreatography (MRCP) and percutaneous transhepatic cholangiography (PTC) along with percutaneous transhepatic biliary drainage (PTBD) stenting in obstructive jaundice, while also incorporating the comparison of ultrasonography (USG) and computed tomography (CT) findings.

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Background Cochlear implant surgery is a complex procedure influenced by the anatomical structures of the temporal bone. Preoperative imaging using CT and MRI can provide critical insights into the surgical challenges that may be encountered. This study aims to evaluate the role of CT and MRI in preoperative assessment to predict the difficulty of cochlear implant surgery in terms of surgical time.

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  • The study compares dynamic contrast-enhanced computed tomography (DCE-CT) and conventional contrast-enhanced computed tomography (CE-CT) for evaluating neck lesions, suggesting that DCE-CT may offer better diagnostic accuracy due to its ability to assess tissue dynamics over time.
  • Conducted on 100 patients, the research found that DCE-CT identified more lesions and had higher sensitivity (93.33%) and specificity (96.00%) compared to CE-CT (sensitivity 86.67%, specificity 92.00%).
  • DCE-CT was shown to improve treatment plans in 40% of cases and resulted in better patient outcomes (75% improvement) compared to CE-CT
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Introduction The prevalence and clinical significance of fetal posterior cerebral artery (FPCA) variants are studied using magnetic resonance imaging (MRI) at Saveetha Medical College. This research focuses on the fetal origin of the posterior cerebral artery (PCA), a condition where the posterior communicating artery (PComA) is larger than the P1 segment of the PCA, affecting cerebral hemodynamics and associated with various cerebrovascular pathologies. Materials and methods This retrospective analysis employed MRI records from the Department of Radio Diagnosis at Saveetha Medical College, conducted between January 2013 and December 2023.

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Introduction Preeclampsia is a serious complication marked by antepartum hemorrhage, resulting in severe maternal and fetal complications. Predicting this condition using placental dysfunction assessments, such as uterine artery Doppler ultrasound, is challenging due to the placenta's evolving structural and biochemical characteristics throughout different stages of pregnancy. Objectives To determine the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the uterine artery Doppler Pulsatility Index (PI) and Resistive Index (RI) in predicting preeclampsia.

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Background: Endometrial cancer (EC) is the most common gynecological malignancy. Accurate preoperative staging is essential for guiding treatment. The depth of myometrial invasion is a key prognostic factor.

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Background While two-dimensional (2D) turbo spin echo (TSE) sequences offer better through-plane resolution than three-dimensional (3D) isotropic TSE sequences images, with a narrower thickness of the slice, 3D isotropic TSE sequences are known to have a weaker in-plane resolution as well as blurring of the image. These elements may make it more difficult to distinguish between nearby structures that may affect nerve roots and small nerve roots during spinal imaging. This study aimed to analyze the accuracy of T2 TSE sequence and volumetric isotropic TSE acquisition in determining the indentation of nerve roots and perineural diseases such as nerve sheath tumors and Tarlov cysts.

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Lemmel syndrome, characterized by biliary and pancreatic duct obstruction secondary to a periampullary duodenal diverticulum (PAD), remains a rare and often overlooked diagnosis. Although duodenal diverticula are found in approximately 23% of the population, only about 5% of these cases lead to complications such as obstructions. A new case of Lemmel syndrome is demonstrated in the article about a middle-aged woman with chronic epigastric pain and right upper abdominal quadrant initially misdiagnosed as cholelithiasis.

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  • MRCP is an imaging technique essential for studying pancreaticobiliary diseases, and this study tested how three oral contrast agents (date syrup, hematinic syrup, and pineapple juice) affect image quality.
  • The study involved 90 participants divided into three groups, each ingesting different oral contrasts before being scanned using 1.5 Tesla MRI, measuring signal-to-noise and contrast-to-noise ratios.
  • Results showed that while all three agents improved image quality, pineapple juice had the best signal-to-noise ratio, followed by date syrup and hematinic syrup, with no adverse effects reported from the participants.
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Background Cerebrospinal fluid (CSF) dynamics play a crucial role in maintaining the homeostasis of the central nervous system (CNS). Any disruption in CSF flow can lead to various congenital and acquired conditions, impacting neurological function and overall health. This study aims to analyze the significance of phase-contrast MRI in evaluating abnormalities in CSF flow and its diagnostic utility in various CSF-related disorders.

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Background Renal insufficiency, a critical concern in native and transplant kidneys, necessitates effective screening modalities for evaluation and management. Grayscale sonography has been a cornerstone in renal diagnostics, providing basic anatomical insights such as renal length, cortical thickness, and collecting system dilatation. Despite technological advancements, its impact on the differential diagnosis or management of renal disease remains limited, often showing normal findings in the presence of severe renal dysfunction.

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Background: The morphology of the distal femur's intercondylar notch has been implicated in the susceptibility to and severity of cruciate ligament injuries. While previous research has primarily focused on isolated anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL) injuries, the relationship between notch morphology and combined cruciate injuries remains less understood.

Objective: This study aimed to explore the association between femoral notch morphology and the severity of combined cruciate ligament injuries in adult males.

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