Oral squamous cell carcinoma (OSCC) is a prevalent cancer, and understanding its mechanisms, particularly the role of the protein ORM1 in promoting angiogenesis, is important for comprehending tumor growth.
This study aimed to assess ORM1 expression and microvascular density in 45 OSCC samples categorized by their histological grade.
Results showed that while ORM1 and CD34 markers were present in all cases, their expression did not significantly differ across grades, indicating that ORM1's role may relate more to immune regulation rather than angiogenesis in OSCC.