Structural organization of the human complexin 2 gene (CPLX2) and aspects of its functional activity.

We report here on the in vitro and in silico characterization of the organization of the human complexin 2 (CPLX2) gene. This encodes for a protein of 134 amino acid residues, contains five exons, is localized on human chromosome 5q35.3, and spans more than 87 kb.

Hmob3 brain-specific sequence is a part of phylogenetically conserved human MAP1B gene 3'-untranslated region.

Using in vitro and in silico approaches, we demonstrate that the Hmob3 brain-specific sequence is a part of the extended human MAP1B gene 3'UTR encoded by the portion of the exon 7. Previously we had isolated the 1.4 kb Hmob3 clone (Acc.