Publications by authors named "Nataliia Pustova"
Objective: Aim: To study IL-1β, IL-6, IL-8, IL-10 blood serum levels and their relationship with colon tissue prostanoids in experimental ulcerative colitis.
Patients And Methods: Materials and Methods: Blood serum interleukins and colon tissue prostanoids were determined by enzyme immunosorbent assay on three groups of WAG population rats (1st control group - rectal saline injection; 2nd control group - 50% ethanol injection; experimental group - injection of 2,4-dinitrobenzene-sulfonic acid in 50% ethanol).
Results: Results: The increased levels of all interleukins both in 2nd control and experimental groups versus 1st control group were found.
Objective: The aim of this study was to determine the level of ROS production by blood leukocytes of rats with PCOS under the conditions of intermittent cold exposure.
Patients And Methods: Materials and methods: In the study, 40 immature female rats of the WAG population at the age of 27 days with a body weight of 80-90 g were used. Five groups were formed (8 animals in each group).
Objective: The aim: To assess reactive oxygen species production by leukocytes and their viability in rats with chronic colitis.
Patients And Methods: Materials and methods: Reactive oxygen species production was estimated in leukocytes, isolated from rats with Dextran Sulfate Sodium-induced chronic colitis and control rats, by flow cytometry using the fluorescent probe 2',7'-dichlorodihydrofluorescein diacetate. Leukocyte viability and apoptosis stages were assessed by flow cytometry using annexin V and 7-aminoactinomycin D staining.