THE ROLE OF NITRIC OXIDE AND PEROXYNITRITE IN THE ERYTHEMAL PERIOD OF ULTRAVIOLET-INDUCED SKIN DAMAGE.

Objective: The aim: To study the activity of inducible NO synthase in the blood, the content of NO metabolites and peroxynitrite in the skin and blood of guinea pigs during erythema periods after local ultraviolet skin irradiation.

Patients And Methods: Materials and methods: The studies were carried out on 24 guinea pigs, subjected to local ultraviolet irradiation. The control group consisted of intact guinea pigs (n=6).

Effect of local UV radiation on the morphofunctional state of the skin of guinea pigs in early and remote periods after irradiation.

Objective: The aim is to establish the features of morphological and morphometric changes in the skin of guinea pigs in erythemal, early post-erythemal and late post-erythemic periods after local ultraviolet irradiation.

Patients And Methods: Materials and methods: Studies were conducted on 54 albino guinea pigs weighing 400-500 g. Ultraviolet erythema was caused by irradiation in 1 minimum erythemal dose.