Publications by authors named "Natalie Valentino"

Article Synopsis
  • Clinical pharmacist practitioners (CPPs) are vital in interdisciplinary teams, especially for Veterans with substance use disorders, homelessness, and complex medical needs.
  • A study analyzed CPP activities in a VA primary care clinic, revealing they handled 228 patients with substantial involvement in care, including in-clinic, phone visits, and chart reviews.
  • CPPs focused on managing various issues like mental health and substance use disorders, administering medications, and performing opioid risk mitigation measures, suggesting their role could be expanded in other primary care environments.
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Kratom is a substance that when ingested produces an opioid-like effect. As kratom continues to gain popularity, increasing numbers of cases of addiction, dependence, and adverse events have been reported, as well as an increase in mortality associated with its use. George E.

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Article Synopsis
  • * The Vulnerable Veteran Innovative Patient-Aligned Care Team (PACT) Initiative is a team-based primary care model aimed at integrating care for veterans facing substance use disorders, mental health issues, and complex health needs.
  • * Ongoing evaluation of the VIP initiative is necessary to assess its effectiveness and potential for broader implementation in improving care for vulnerable patients.
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Mutations in leucine-rich repeat kinase 2 (LRRK2), which are associated with autosomal dominant Parkinson's disease, elicit progressive dendrite degeneration in neurons. We hypothesized that synaptic dysregulation contributes to mutant LRRK2-induced dendritic injury. We performed in vitro whole-cell voltage clamp studies of glutamatergic receptor agonist responses and glutamatergic synaptic activity in cultured rat cortical neurons expressing full-length wild-type and mutant forms of LRRK2.

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