Perioperative Administration of Emend (Aprepitant) at a Tertiary Care Children's Hospital: A 12-Month Survey.

Introduction: Aprepitant (Emend) is a novel antiemetic agent that works through antagonism of neurokinin-1 (NK-1) receptors. To date, there are limited data regarding its use to prevent postoperative nausea and vomiting (PONV) in children. We retrospectively reviewed our initial 12-months experience with aprepitant after it was made available for perioperative use.