Predictive Factors of Chronic Post-Surgical Pain at 6 Months Following Knee Replacement: Influence of Postoperative Pain Trajectory and Genetics.

Background: The frequency of chronic postsurgical pain (CPSP) after knee replacement remains high, but might be decreased by improvements to prevention.

Objectives: To identify pre- and postsurgical factors predictive of CPSP 6 months after knee replacement.

Study Design: Single-center prospective observational study.