Publications by authors named "Natalie Poliektov"
We compared serum anti-Mullerian hormone (AMH) levels in women with sickle cell disease (SCD) (n = 152) to those of Black comparison women (n = 128) between the ages of 20 and 45 years and evaluated the impact of hydroxyurea (HU) and iron overload on ovarian reserve in those with SCD. SCD treatment was abstracted from medical records. Linear regression models were fit to examine the relationship between log(AMH) and SCD, adjusting for age.
View Article and Find Full Text PDFObjective: To compare the risk of severe maternal morbidity (SMM) from the delivery admission to 42 days' postdischarge among persons with sickle cell disease (SCD) to those without SCD.
Study Design: This retrospective cohort study included deliveries ≥20 weeks' gestation at an urban safety net hospital in Atlanta, GA from 2011 to 2019. The exposure was SCD diagnosis.
Article Synopsis
- The study investigates the link between socioeconomic status (SES) and maternal serum cytokine profiles during pregnancy, focusing on how lower SES correlates with chronic inflammation.
- Researchers compared cytokine levels in pregnant women from low SES (Medicaid-insured) and high SES (privately-insured) backgrounds, finding significant differences in inflammatory markers.
- Results indicated higher levels of IL-6 (linked to chronic inflammation) in the low SES group and lower levels of IL-1β and TNF-α, suggesting that SES may impact inflammation and thereby affect pregnancy outcomes.
Article Synopsis
- Pregnant patients are more vulnerable to severe COVID-19 outcomes compared to non-pregnant individuals, and high levels of inflammatory markers have been linked to adverse pregnancy events.
- A study analyzed the inflammatory cytokine profiles of pregnant women who had acute or past SARS-CoV-2 infections, focusing on those with positive COVID-19 test results within a certain timeframe.
- The results showed that patients with acute/post-acute infections had higher levels of specific inflammatory markers (IL-10, IL-1β, IL-8) compared to those with previous exposure, highlighting differences in immune response during pregnancy.
The majority of pediatric human immunodeficiency virus (HIV) infections are the result of vertical transmissions that occur during pregnancy, childbirth, and breastfeeding. The treatment of all pregnant persons living with HIV remains a global health initiative. Early and consistent use of antiretroviral therapy throughout pregnancy and childbirth drastically reduces the risk of perinatal transmission of HIV, resulting in fewer children living with the disease worldwide.
View Article and Find Full Text PDFBleeding cervical varices in pregnancy: A case report and review of the literature.
J Neonatal Perinatal Med
February 2022
Background: Venous varicosities are a relatively common finding during pregnancy. Rarely, varices can arise in the cervix and cause life-threatening maternal hemorrhage. This article offers an example of a patient who was diagnosed with bleeding cervical varices during pregnancy and summarizes the diagnosis and treatment strategies for the 20 other reported cases in the literature.
View Article and Find Full Text PDF