Many women undergoing fertility treatment make poor lifestyle choices that may affect treatment outcome.

Study Question: What are the lifestyle choices and dietary aspects of women about to undergo fertility treatment in New Zealand?

Summary Answer: A considerable proportion of women about to undergo fertility treatment make poor lifestyle choices, including the consumption of alcohol and caffeine.

What Is Known Already: Women undergoing fertility treatment are highly motivated to achieve pregnancy, but there are relatively few published data on their lifestyle, lifestyle changes or dietary aspects.

Study Design, Size, Duration: This was a cross-sectional study of 250 women aged 20-43 years, taking place between March 2010 and August 2011.

Discovery and mechanistic characterization of a novel selective nuclear androgen receptor exporter for the treatment of prostate cancer.

Despite the success of medical strategies to reduce androgen levels in the treatment of prostate cancer, this disease invariably relapses to a castrate-resistant state that is generally fatal. Although it had been thought that androgen-insensitive cancers no longer relied on the androgen receptor (AR) for growth and survival, it is now clear that this is not the case. Because relapses are known to occur by many mechanisms that keep the AR functionally active, strategies to block AR accumulation in the nucleus may be therapeutically useful.