Publications by authors named "Natalie Koh Si Ya"
Article Synopsis
- About 50% of the susceptibility to atherosclerotic cardiovascular disease (ASCVD) is genetic, with individual genetic variants usually having a small impact on risk.
- Recent studies indicate that combining these genetic variations into polygenic risk scores (PRS) can improve risk assessment compared to traditional factors.
- Current PRS are mainly based on data from individuals of European ancestry, leading to challenges in their effectiveness for non-European populations, particularly in the Asia-Pacific region, which highlights a need for tailored PRS in clinical settings.
Objectives: Motivators and barriers are pivotal factors in the adoption of health behaviors. This study aims to identify patterns of the motivators and barriers influencing heart health behaviors among multi-ethnic Asian adults with behavior-modifiable risk factors for heart disease, namely obesity, physical inactivity and smoking.
Methods: A population-based survey of 1,000 participants was conducted in Singapore.