Effects of Different Loading Programs on Finger Strength in Rock Climbers.

Background: Climbing places high loads through the hands and fingers, and climbers may benefit from specific finger strength training (hangboarding) protocols. The purpose of this study was to evaluate the effect of a 10-minute low intensity hangboard finger strengthening protocol ("Abrahangs"), compared with the generally accepted Max Hangs protocol for training maximal grip strength.

Methods: We retrospectively evaluated the change in grip strength and Strength: Weight following Max Hangs, Abrahangs, or the two protocols performed concurrently in rock climbers who used the Crimpd app to log their training.

Role of parvalbumin in fatigue-induced changes in force and cytosolic calcium transients in intact single mouse myofibers.

One of the most important cytosolic Ca buffers present in mouse fast-twitch myofibers, but not in human myofibers, is parvalbumin (PV). Previous work using conventional PV gene () knockout (PV-KO) mice suggests that lifelong ablation increases fatigue resistance, possibly due to compensations in mitochondrial volume. In this work, ablation was induced only in adult mice (PV-KO), and contractile and cytosolic Ca responses during fatigue were studied in isolated muscle and intact single myofibers.

Role of IL-33 receptor (ST2) deletion in diaphragm contractile and mitochondrial function in the Sugen5416/hypoxia model of pulmonary hypertension.

Pulmonary arterial hypertension (PAH) is a progressive disease of the pulmonary vasculature that leads to right ventricular failure. Skeletal muscle maladaptations limit physical activity and may contribute to disease progression. The role of alarmin/inflammatory signaling in PAH respiratory muscle dysfunction is unknown.