Publications by authors named "Natalie J Ameral"
Genome Assembly of a Living Fossil, the Atlantic Horseshoe Crab Limulus polyphemus, Reveals Lineage-Specific Whole-Genome Duplications, Transposable Element-Based Centromeres, and a ZW Sex Chromosome System.
Kate R Castellano Michelle L Neitzey Andrew Starovoitov Gabriel A Barrett Noah M Reid Natalie J Ameral
Mol Biol Evol
February 2025
Horseshoe crabs, considered living fossils with a stable morphotype spanning ∼445 million years, are evolutionarily, ecologically, and biomedically important species experiencing rapid population decline. Of the four extant species of horseshoe crabs, the Atlantic horseshoe crab, Limulus polyphemus, has become an essential component of the modern medicine toolkit. Here, we present the first chromosome-level genome assembly, and the most contiguous and complete assembly to date, for L.
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- Sleep plays a crucial role in heart health, especially after a heart attack (myocardial infarction), by influencing inflammatory responses and healing processes.
- After a heart attack, certain immune cells (monocytes) are recruited to the brain to promote sleep, which helps reduce harmful stress on the heart and supports recovery.
- Disruption of sleep can worsen heart function and increase the risk of further cardiovascular issues, as poor sleep can reprogram immune cells in a way that enhances inflammation and hinders the healing process.