Publications by authors named "Natalie Hinterholzer"

There is emerging evidence that sampling the blood-oxygen-level-dependent (BOLD) response with high temporal resolution opens up new avenues to study the in vivo functioning of the human brain with functional magnetic resonance imaging. Because the speed of sampling and the signal level are intrinsically connected in magnetic resonance imaging via the T1 relaxation time, optimization efforts usually must make a trade-off to increase the temporal sampling rate at the cost of the signal level. We present a method, which combines a sparse event-related stimulus paradigm with subsequent data reshuffling to achieve high temporal resolution while maintaining high signal levels (HiHi).

View Article and Find Full Text PDF

One of the main advantages of three-dimensional (3D) magnetic resonance imaging (MRI) is the possibility of isotropic voxels and reconstructed planar cuts through the volumetric data set in any orientation with multiplanar reformation software through real-time evaluation. For example, reformats by the radiologist during reporting allows exploitation of the full potential of isotropic 3D volumetric acquisition or through standardized retrospective reformats of thicker predefined slices of an isotropic volumetric data set by technologists. The main challenges for integrating 3D fast spin echo (FSE) and turbo spin-echo (TSE) MRI in clinical practice are a long acquisition time and some artifacts, whereas for integrating 3D gradient-recalled echo protocols, the main challenges are lower signal-to-noise ratios (SNRs) and the inability to produce intermediate, and T2-weighted contrast.

View Article and Find Full Text PDF

Objectives: Through-slice chemical shift artifacts in state-of-the-art turbo-spin-echo (TSE) images can be significantly more severe at 7 T than at lower field strengths. In musculoskeletal applications, these artifacts appear similar to bone fractures or neoplastic bone marrow disease. The objective of this work was to explore and reduce through-slice chemical shift artifacts in 2-dimensional (2D) TSE imaging at 7 T.

View Article and Find Full Text PDF

Compared to computed tomography (CT), magnetic resonance imaging (MRI) provides superior visualization of the soft tissue. Recently, the first 7 Tesla (7 T) MRI scanner was approved for clinical use, which will facilitate access to these ultra-high-field MRI scanners for noninvasive examinations and scientific studies on decedents. 7 T MRI has the potential to provide a higher signal-to-noise ratio (SNR), a characteristic that can be directly exploited to improve image quality and invest in attempts to increase resolution.

View Article and Find Full Text PDF