Predictors and outcomes of restenosis following tibial artery endovascular interventions for critical limb ischemia.

Objective: Restenosis following tibial artery endovascular interventions (TAEIs) is thought to be benign but is not well characterized. This study examines the consequences and predictors of recurrent stenosis of TAEIs for critical limb ischemia.

Methods: All TAEIs for critical limb ischemia performed between 2004 and 2010 were retrospectively reviewed.

Impact of gender and age on outcomes of tibial artery endovascular interventions in critical limb ischemia.

Background: Female sex and older age are known risk factors for adverse outcomes in peripheral artery disease. This study reports on the outcomes of tibial artery endovascular intervention (TAEI) by age and gender in patients treated for critical limb ischemia.

Methods: All TAEIs for tissue loss or rest pain (Rutherford classes 4, 5, and 6) from 2004 to 2010 were retrospectively reviewed.

Expression of antigen processing and presenting molecules in brain metastasis of breast cancer.

Defects in human leukocyte antigen class I antigen processing machinery (APM) component expression can have a negative impact on the clinical course of tumors and the response to T cell-based immunotherapy. Since brain metastases of breast cancer are of increasing clinical significance, the APM component expression levels and CD8(+) T cell infiltration patterns were analyzed in primary breast and metastatic brain lesions of breast cancer by immunohistochemistry. Comparison of unpaired 50 primary and 33 brain metastases showed lower expression of β2-microglobulin, transporter associated with antigen processing (TAP) 1, TAP2 and calnexin in the brain lesions.

Parotid tumor size predicts proximity to the facial nerve.

Objectives/hypothesis: Parotid surgery mandates that every effort be made to identify and preserve the integrity of the facial nerve. A simple method of predicting the proximity of the nerve to the capsule of the tumor preoperatively may benefit surgical planning and patient counseling. We hypothesized that tumor diameter would be an easily available method to predict nerve proximity to the capsule.

Endovascular repair of multiple infrageniculate aneurysms in a patient with vascular type Ehlers-Danlos syndrome.

Patients with vascular type Ehler-Danlos syndrome can develop aneurysms in unusual locations. We describe the case of a 33-year-old woman with vascular type Ehlers-Danlos syndrome who developed metachronous tibial artery aneurysms that were sequentially treated with endovascular means.