Publications by authors named "Natalie B Gulrajani"
Maternal Prenatal Use of Alcohol, Tobacco, and Illicit Drugs and Associations with Childhood Cancer Subtypes.
Cancer Epidemiol Biomarkers Prev
March 2024
Background: The association between childhood cancer risk and maternal prenatal substance use/abuse remains uncertain due to modest sample sizes and heterogeneous study designs.
Methods: We surveyed parents of children with cancer regarding maternal gestational use of tobacco, alcohol, and illicit drugs, using a Likert-type scale, and demographic, perinatal, and clinical variables. Multivariable log-Poisson regression assessed differences in frequency of prenatal substance use across fifteen childhood cancer subtypes, adjusting for birthweight, gestational age, and demographic factors.
Objectives: To investigate the association between assisted reproductive technology (ART) use and childhood cancer subtype.
Study Design: We deployed a cross-sectional survey of 1701 parents of children with cancer about their ART use, demographics, and gestational and perinatal factors. Multivariable logistic regression modeled the association between ART use, birthweight and multiple gestation status with childhood cancer, by subtype.
Article Synopsis
- From the 1870s to the early 20th century, physicians commonly used nutritive enemata as a treatment for gastrointestinal issues, including bowel obstructions, and even administered it to notable figures like Presidents Garfield and McKinley.
- This practice gained traction during a time of growing interest in both allopathic medicine and nutritional research, with many believing in its effectiveness despite ongoing debates about the methods and ingredients used.
- However, by the early 20th century, advancements in biochemistry revealed that rectal nutrition provided minimal calories or protein, leading to its decline in favor of intravenous hydration and later total parenteral nutrition.