Publications by authors named "Natalie A M Cooper"

All gynaecology departments should provide a dedicated outpatient hysteroscopy service to aid care of women and people with abnormal uterine bleeding, reproductive problems, and insertion/retrieval of intrauterine devices. [Grade A] Written information should be provided to the woman prior to their appointment. This should include details about the procedure, the benefits and risks, advice regarding pre-operative analgesia, as well as alternative options for care and contact details for the hysteroscopy unit.

View Article and Find Full Text PDF

Objective: This work contributed to the development of a core outcome set (COS) for heavy menstrual bleeding (HMB). The objective was to determine which research outcomes best reflect how HMB affects women's lives and to identify additional research outcomes, not previously reported. It was important to explore and record participants' reasoning for prioritising outcomes and use this information to reinforce the patients' voice during later phases of the COS development.

View Article and Find Full Text PDF

Objective: To develop a core outcome set for heavy menstrual bleeding (HMB).

Design: Core outcome set (COS) development methodology described by the COMET initiative.

Setting: University hospital gynaecology department, online international survey and web-based international consensus meetings.

View Article and Find Full Text PDF

Evaluation studies of outcomes used in clinical research and their consistency are appearing more frequently in the literature, as a key part of the core outcome set (COS) development. Current guidance suggests such evaluation studies should use systematic review methodology as their default. We aimed to examine the methods used.

View Article and Find Full Text PDF

Introduction: Fetal fibronectin (fFN) is a validated test for assessing risk of preterm birth for women presenting with symptoms. Our aim was to evaluate the accuracy of fFN to detect the risk of preterm birth in asymptomatic women.

Material And Methods: Searches were conducted to identify studies where fFN was performed in asymptomatic women beyond 22 weeks' gestation.

View Article and Find Full Text PDF

Objective: The aim of this study was to identify what components of a postpartum lifestyle intervention would engage postpartum mothers who had a diagnosis of gestational diabetes.

Study Design: Two online surveys were conducted, one involving postnatal mothers with GDM (n=83), and a second for health professionals (n=46).

Results: Seventy-eight percent of mothers were aware that healthy eating, exercise and weight management were all important to reduce risk of subsequent type 2 diabetes.

View Article and Find Full Text PDF

Uterine polyps can cause abnormal bleeding in women. Conventional practise is to remove them under general anaesthesia but advances in technology have made it possible to perform polypectomy in the office setting. We conducted a patient-preference study to explore women's preferences for treatment setting and to evaluate the effectiveness and treatment experience of women undergoing uterine polypectomy.

View Article and Find Full Text PDF

Introduction: Anemia in pregnancy affects 25% of all pregnancies in Europe with iron deficiency affecting even more. Despite supplementation, iron deficiency persists. This review will assess the effect on serum ferritin (iron stores) and hemoglobin (oxygen-carrying capacity) following iron supplementation in pregnant women with anemic and non-anemic iron deficiency.

View Article and Find Full Text PDF

Hysteroscopy is now an ambulatory procedure, having moved from a conventional day-case operating theatre environment to the outpatient clinic setting. Outpatient hysteroscopy can be used as a diagnostic test and as a therapeutic modality for women presenting with abnormal uterine bleeding. In many cases women can be diagnosed and treated efficiently during a single hospital appointment.

View Article and Find Full Text PDF

Introduction: Guidelines report the quality of the evidence used when formulating recommendations to ensure transparency and allow end-users to assess the estimates of effect that underlie the recommendation. The aim of this study was to investigate the differences in grading of evidence quality between the Scottish Intercollegiate Guideline Network (SIGN) model and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) method.

Materials And Methods: The GRADE system was used to create evidence profiles for recommendations from a guideline that used the SIGN method to assess the quality of evidence.

View Article and Find Full Text PDF

Objective: To compare the effectiveness and acceptability of outpatient polypectomy with inpatient polypectomy.

Design: Pragmatic multicentre randomised controlled non-inferiority study.

Setting: Outpatient hysteroscopy clinics in 31 UK National Health Service hospitals.

View Article and Find Full Text PDF

Purpose Of Review: The aim of this review was to evaluate recently published review articles which examine the use of nutritional supplements to prevent preterm birth (PTB) by modifying vaginal bacteria.

Recent Findings: Probiotics, vitamin D and vitamin C were all identified as nutritional supplements that have the potential to alter bacterial flora and consequently reduce PTB and treat or prevent genital infections. Evidence shows that probiotics may reduce the incidence of PTB as well as being effective at treating bacterial vaginosis, a known cause for PTB.

View Article and Find Full Text PDF

Background: Heavy menstrual bleeding (HMB) and post-menopausal bleeding (PMB) together constitute the commonest gynaecological presentation in secondary care and impose substantial demands on health service resources. Accurate diagnosis is of key importance to realising effective treatment, reducing morbidity and, in the case of PMB, reducing mortality. There are many tests available, including transvaginal scan (TVS), endometrial biopsy (EBx), saline infusion sonography and outpatient hysteroscopy (OPH); however, optimal diagnostic work-up is unclear.

View Article and Find Full Text PDF

Hysteroscopy is a mainstay of modern gynaecologic practice. However, the role of ambulatory hysteroscopy and associated procedures has increased dramatically in recent years. The outpatient setting has associated benefits, both for the patient and economically.

View Article and Find Full Text PDF

Objective: To assess the effect of distension medium on pain during outpatient hysteroscopy.

Design: Systematic review and meta-analysis.

Setting: Outpatient hysteroscopy clinics.

View Article and Find Full Text PDF

Objective: To compare the effects of different types of local anaesthetic for pain control during outpatient hysteroscopy.

Design: Systematic review and meta-analysis of randomised controlled trials.

Setting: Outpatient hysteroscopy clinics.

View Article and Find Full Text PDF