Burkholderia thailandensis Methylated Hydroxyalkylquinolines: Biosynthesis and Antimicrobial Activity in Cocultures.

The bacterium produces an arsenal of secondary metabolites that have diverse structures and roles in the ecology of this soil-dwelling bacterium. In coculture experiments, strain E264 secretes an antimicrobial that nearly eliminates another soil bacterium, strain 168. To identify the antimicrobial, we used a transposon mutagenesis approach.