Publications by authors named "Natalia V Maluchenko"
Article Synopsis
- Human PARP1 plays a key role in regulating transcription by helping RNA polymerase II (Pol II) navigate through nucleosomes in the presence of NAD+.
- PARP1's catalytic activity is crucial for this process, as it helps form "open" complexes that allow Pol II to progress along nucleosomal DNA.
- The anti-cancer drug olaparib inhibits PARP1’s function, which reveals the importance of PARP1's interactions with histones during transcription through chromatin.
Aggression is a heterogeneous heritable psychological trait, also influenced by environmental factors. Previous studies, mostly conducted on male population, have found some associations of the aggression with the polymorphisms of genes, regulating the activity of serotonin (5-HT) in the brain. However, psychological as well as biochemical manifestations of the aggression are different in males and females.
View Article and Find Full Text PDFToxic lectins of European mistletoe Viscum album L.--MLI (viscumin), MLII and MLIII--are present in water extracts of this plant. Earlier we have cloned the full-length gene of MLIII precursor [A.
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