Publications by authors named "Natalia V Akulenko"
Article Synopsis
- The nascent polypeptide-associated complex (NAC) is a crucial ribosome-associated protein involved in protein folding and sorting, and it is conserved across eukaryotic organisms.
- Researchers have identified germline-specific NACαβ paralogs (gNACs), which have unique protein structures in their α and β subunits, particularly longer regions that may be phosphorylated.
- The study suggests that these gNACs play a role in the coordination of protein regulation within germline cells, and there appears to be an interaction between gNACs and the commonly expressed NAC subunits that impacts organismal development.
Eur J Cell Biol
September 2016
Article Synopsis
- The RNA helicase Spindle-E (Spn-E) is crucial for the piRNA silencing process in Drosophila, specifically in the reproductive organs where it helps prevent retrotransposon mobilization and gene derepression.*
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- Research on spn-E heterozygous flies showed a significant presence of piRNA ping-pong pairs linked to Su(Ste) transcripts, but these levels dropped sharply in spn-E mutant flies.*
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- The absence of Spn-E led to a notable decrease in key proteins involved in the ping-pong mechanism, Aubergine and AGO3, suggesting that Spn-E might play a role in post-transcriptional regulation rather than affecting their overall synthesis.*
Article Synopsis
- - The genome of the lytic bacteriophage tf, which targets Pseudomonas putida PpG1, has been fully sequenced and consists of 46,267 base pairs, revealing a structure similar to other Pseudomonas phages like PaP3 and LUZ24, with 39 of its genes having counterparts in these phages.
- - Despite similarities, tf is considered an evolutionary distinct member of the LUZ24-like group due to low genetic homology with other phages, featuring unique characteristics like a specific end structure and 14 single-chain interruptions (nicks) in its DNA.
- - The identified nicks, particularly within a consensus sequence, occur in a large percentage of the
