Prognostic value of TH1/TH2 cytokines in infants with wheezing in a three year follow-up study.

Introduction: The immune system is known to play a key role in the development of viral-induced wheeze, but the pattern of cytokine response is not clear. The aim of the study was to determine whether plasma cytokine levels during the acute wheezing illness in infants are associated with the subsequent development of persistent recurrent wheezing (PRW).

Material And Methods: 43 infants admitted to Iashvili Central Children Hospital, Tbilisi, Georgia, were selected.