Prognostic implication of TERT promoter mutation and circulating tumor cells in muscle-invasive bladder cancer.

Purpose: Current clinical prognostic factors are not accurate enough to identify and monitor those muscle-invasive bladder cancer (MIBC) patients at high risk of progression after radical cystectomy (RC). Here, we determined genetic alterations in the tumor and circulating tumor cell (CTC) enumeration to find biomarkers useful for the management of MIBC after RC.

Methods: Thirty-nine MIBC patients undergoing RC were included.

Effects of resective epilepsy surgery on the social determinants of health.

Objectives: The aim of this study is to analyze changes in the Social Determinants of Health (SDH) in patients undergoing epilepsy surgery in Mexico.

Materials And Methods: We retrospectively analyzed 102 adult patients who underwent brain resection for focal epilepsy (2002-2014) with at least 4 years of follow-up; described clinical variables (age, race, sex, age of onset of epilepsy, age at the time of surgery, type of surgery, side of surgery) and sociodemographic variables including education, income, race/ethnicity, occupation, and marital status.

Statistical Analysis: Descriptive and inferential statistics were used.