A pilot study of changes in urinary podocalyxin levels during normal pregnancy and labor.

Increased urinary podocalyxin, a surrogate marker of podocyte detachment, has been shown in preeclampsia and eclampsia, but there is a paucity of data of the effect of normal pregnancy on its urinary excretion. We aimed to describe these changes in this pilot study. Urine podocalyxin levels were measured in 115 pregnant women.

Long term follow up of biomarkers of podocyte damage and renal function in patients with and without preeclampsia.

Introduction: preeclampsia can be associated with future renal disease.

Objectives: To measure changes in renal function overtime in patients with preeclampsia.

Methods: urine and serum samples from eleven patients with preeclampsia and eight patients with a normal pregnancy were obtained during pregnancy, postpartum, and 3 years after delivery.

Urinary podocalyxin as a marker of preeclampsia in a Hispanic population.

Background: Preeclampsia is associated with significant materno-fetal morbidity and mortality. Podocyturia due to podocyte damage seems to be associated with the disease. The objective of this study was to evaluate the usefulness of urinary podocalyxin as a marker of preeclampsia in a Hispanic population.