Publications by authors named "Natalia Sedova"

Article Synopsis
  • * Specific cytokines such as IL-1b, IL-6, and TNF-a were associated with both higher levels of harmful gut bacteria and the severity of cirrhosis symptoms like ascites, suggesting a connection between gut health and liver disease progression.
  • * The results indicate that certain gut bacteria populations correlate directly with inflammatory cytokine levels, pointing to a potential link between gut dysbiosis and systemic inflammation in cirrhosis patients.
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Our aim was to study the association of endothelial dysfunction biomarkers with cirrhosis manifestations, bacterial translocation, and gut microbiota taxa. The fecal microbiome was assessed using 16S rRNA gene sequencing. Plasma levels of nitrite, big endothelin-1, asymmetric dimethylarginine (ADMA), presepsin, and claudin were measured as biomarkers of endothelial dysfunction, bacterial translocation, and intestinal barrier dysfunction.

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