Publications by authors named "Natalia Sabina Dos Santos Galvao"

Article Synopsis
  • Aspirin, discovered in 1899 by Felix Hoffman, has been a top-selling drug for 125 years, serving as a major success in the pharmaceutical industry.
  • This review highlights various analytical methods used to study Acetylsalicylic Acid (ASA) and their relevance to current sustainable chemistry practices.
  • The predominant analytical techniques for ASA are HPLC and UV-Vis, mainly involving traditional solvents like methanol and acetonitrile, suggesting a need for greener solutions in the evaluation of this long-standing medication.
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Background: Ivermectin (IVE), a broad-spectrum antiparasitic, is used in human and animal health. Analytical methods for evaluating IVE in pharmaceutical products are found in the literature and in official compendiums. However, the vast majority of them do not have an eco-friendly approach.

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The literature reveals gaps in the availability of green analytical methods for assessing products containing gatifloxacin (GFX), a fluoroquinolone. Presently, method development is supported by tools such as the National Environmental Methods Index (NEMI) and Eco-Scale Assessment (ESA), which offer objective insights into the environmental friendliness of analytical procedures. The objective of this work was to develop and validate a green method by the NEMI and ESA to quantify GFX in eye drops using HPLC.

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