Publications by authors named "Natalia Ponte Fernandes"
Development of and mutations for integrase inhibitor resistance in a patient undergoing treatment for pulmonary tuberculosis: A case report.
Luís Arthur Brasil Gadelha Farias Melissa Fiuza Saboya Natália Ponte Fernandes Lauro Vieira Perdigão Neto Erico Antonio Gomes de Arruda
SAGE Open Med Case Rep
December 2023
Article Synopsis
- - The case details a 29-year-old male with HIV and tuberculosis who experienced treatment failure while on dolutegravir, an effective but increasingly challenged drug.
- - After 8 months of therapy, his viral load remained high, and genetic testing revealed mutations associated with resistance to the integrase inhibitor.
- - The findings underscore the need for careful monitoring of treatment adherence and regimen choice for patients co-infected with HIV and TB to prevent resistance and ensure effective management.