Publications by authors named "Natalia Pelet Del Toro"
Article Synopsis
- Lichen planus (LP) is a chronic inflammatory disease affecting the skin and mucous membranes, with a low overall prevalence of about 0.15% among U.S. adults, higher in females compared to males.
- Among over half a million patients studied, 1,098 had LP, with many (53%) receiving no treatment after a year; topical corticosteroids were the most common initial therapy.
- The findings highlight the need for further research on treatment options since patients on systemic immunosuppressants were more likely to continue or switch treatments after a year.
Article Synopsis
- - Lichen planopilaris (LPP) is a type of hair loss that leads to scarring and has symptoms like burning and itching, which can also severely affect mental health, but finding effective treatments is complicated due to limited data on the disease.
- - This study aimed to analyze how common LPP is among US adults and how dermatologists treat it, using the Explorys database and focusing on patients diagnosed from 2016 to 2020.
- - Results showed that out of over 1.4 million patients assessed, 241 were diagnosed with LPP, primarily affecting women, with a prevalence of about 13.4 per 100,000 people. The majority of patients received some form of
Article Synopsis
- * A review of various safety data sources found that the incidence of GI-related adverse reactions from topical clindamycin is extremely low, only 0.000045%.
- * In clinical trials, only 1.4% of participants experienced gastrointestinal AEs, suggesting that concerns about colitis are minimal, although there are limitations in the data's accuracy and generalizability.
Utilization of telemedicine for dermatology has greatly expanded since the start of the COVID-19 pandemic, with over 500 new teledermatology studies published since 2020. An updated review on teledermatology is necessary to incorporate new findings and perspectives, and educate dermatologists on effective utilization. We discuss teledermatology in terms of diagnostic accuracy and clinical outcomes, patient and physician satisfaction, considerations for special patient populations, published practice guidelines, cost effectiveness and efficiency, as well as administrative regulations and policies.
View Article and Find Full Text PDFObjective: Hansen's disease (HD) is a chronic granulomatous infection endemic in the tropics. Its main clinical manifestations involve the cutaneous, nervous, and musculoskeletal systems. Leprosy reactions (LR) are systemic inflammatory and immune-mediated complications of HD.
View Article and Find Full Text PDFBackground: Case identification strategies to conduct population-based studies have not been developed for lichen planus (LP) or lichen planopilaris (LPP).
Objectives: The aim of this study was to assess the validity of using diagnostic codes to establish both a cutaneous (non-oral) LP cohort and an LPP cohort from a large clinical database.
Methods: A retrospective chart review was performed to determine whether patients with ICD-9 or ICD-10 codes for LP and ICD-10 codes for LPP are confirmed cases of LP and LPP.
Article Synopsis
- * Using validated screening tools for related conditions, like psoriatic arthritis, can help improve access to specialists and reduce delays in diagnosis and treatment.
- * While telehealth offers convenience and may enhance care, it should complement, not completely replace, traditional in-person dermatology or rheumatology visits.
The landscape of psoriasis treatments has undergone rapid change within the last decade and the dizzying speed of drug development has not slowed, with 4 notable entries into the psoriasis treatment armamentarium within the last year: tapinarof, roflumilast, deucravacitinib, and spesolimab. Several others are in late-stage development, and these therapies represent new mechanisms, pathways, and delivery systems, meaningfully broadening the spectrum of treatment choices for our patients. However, it can be quite difficult to keep track of all the medication options.
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- This study investigates how often psoriasis patients stop their biologic therapy and looks at the demographics and health characteristics of these patients.
- A total of 77 psoriasis patients who had discontinued biologic therapy at least once were analyzed, revealing that common comorbidities included hypertension and diabetes, while adalimumab and ustekinumab were the most used biologics.
- The main reason for stopping therapy was lack of effectiveness, with insurance coverage also affecting the discontinuation of certain biologics; findings showed no significant links between therapy discontinuation and patient demographics.
Background: Esophageal injuries are rare, life-threatening, events with an overall reported incidence of less than 3%. In rare cases, trauma due to blunt or penetrating injuries cause esophageal perforations, which account for less than 15% of all esophageal injuries.
Materials And Methods: A case-series study was conducted to describe the outcomes and management of all the traumatic esophageal injuries at the Puerto Rico Trauma Hospital (PRTH) from 2000 through 2017.