The Impact of ACTN3 Gene Polymorphisms on Susceptibility to Exercise-Induced Muscle Damage and Changes in Running Economy Following Downhill Running.

This study aimed to investigate if ACTN3 gene polymorphism impacts the susceptibility to exercise-induced muscle damage (EIMD) and changes in running economy (RE) following downhill running. Thirty-five healthy men were allocated to the two groups based on their gene variants: RR and X allele carriers. Neuromuscular function [knee extensor isometric peak torque (IPT), rate of torque development (RTD), and countermovement, and squat jump height], indirect markers of EIMD [muscle soreness, mid-thigh circumference, knee joint range of motion, and serum creatine kinase (CK) activity], and RE (oxygen uptake, minute ventilation, blood lactate concentration, and perceived exertion) for 5-min of running at a speed equivalent to 80% of individual maximal oxygen uptake speed were assessed before, immediately after, and 1-4 days after a 30-min downhill run (-15%).

Effects of resistance training on impulse above end-test torque and muscle fatigue.

New Findings: What is the central question of this study? What role do neuromuscular fatigue mechanisms play in resistance training-induced adaptations of the impulse above end-test torque (IET) after the training period? What is the main finding and its importance? IET and global and peripheral fatigue were increased after a short period of resistance training. Thus, resistance training-induced adaptations in neuromuscular fatigue seem to contribute to enhanced IET after the training period.

Abstract: Short-term resistance training has a positive influence on the curvature constant of the power-duration relationship (W').

Exercise tolerance during muscle contractions below and above the critical torque in different muscle groups.

The objective of this study was to test the hypotheses that end-test torque (ET) (expressed as % maximal voluntary contraction; MVC) is higher for plantar flexors (PF) than knee extensors (KE) muscles, whereas impulse above ET (IET) is higher for KE than PF. Thus, we expected that exercise tolerance would be longer for KE than PF only during the exercise performed above ET. After the determination of MVC, 40 men performed two 5-min all-out tests to determine ET and IET.