Background: Hyaluronic acid is a widely available, biocompatible, polysaccharide with distinguishing physiochemical properties which inspire its application throughout several fields of medicine.
Objective: We aim to investigate the application of hyaluronic acid and its effectiveness throughout several fields of medicine, including several therapies administered and prescribed by general health practitioners.
Methods: We conducted a systematic review on randomized controlled trials about the physiochemical properties of hyaluronic acid and its application through primary care.